肠源性代谢产物氧化三甲胺与糖尿病肾病的相关性研究进展

Research Progress on the Relationship between Intestinal Metabolite Trimethylamine Oxide and Diabetic Kidney Disease

糖尿病肾病(Diabetic kidney disease, DKD)是糖尿病常见慢性并发症之一,是导致我国成人出现肾衰竭的常见原因。肠源性代谢产物氧化三甲胺(Trimetlylamine oxide, TMAO)与DKD的发生、进展的重要因素之一,本文对TMAO与DKD相关研究进行综述,旨在为临床防治DKD提供参考依据。

Diabetic kidney disease (DKD) is one of the common chronic complications of diabetes and the common cause of renal failure in adults in China. Trimethylamine oxide (TMAO), is one of the important factors in the occurrence and progression of DKD. This article reviews the research related to TMAO and DKD, aiming to provide reference for clinical prevention and treatment of DKD.