儿童迁延性细菌性支气管炎治疗的研究进展

Research Progress in the Treatment of Protracted Bacterial Bronchitis in Children

儿童迁延性细菌性支气管炎(Protracted Bacterial Bronchitis, PBB)是一种常见的呼吸道感染性疾病,主要由细菌感染引起,一些患儿会出现症状持续时间延长、反复发作及影响生活质量等问题。近年来,随着分子生物学、免疫学和微生物学等领域的不断发展,对于儿童PBB的治疗研究也取得了一系列重要进展,通过对患儿呼吸道微生物组的深入研究,揭示了其微生物组成和变化规律,为个体化治疗提供了新的思路和方法。本文旨在对儿童迁延性细菌性支气管炎治疗的研究进展进行系统性的综述和分析,以期为临床实践提供更为科学和有效的指导。

Protracted bacterial bronchitis (PBB) in children is a common respiratory infectious disease, which is mainly caused by bacterial infection. Some children may have problems such as prolonged symptom duration, recurrent attacks and impact on quality of life. In recent years, with the continuous development of molecular biology, immunology, and microbiology, a series of important progress has been made in the treatment research of pediatric PBB. Through in-depth research on the respiratory microbiome of pediatric patients, the microbial composition and changes have been revealed, providing new ideas and methods for personalized treatment. This article aims to provide a systematic review and analysis of the research progress in the treatment of protracted bacterial bronchitis in children, in order to provide more scientific and effective guidance for clinical practice.