射血分数保留的心力衰竭诊疗相关进展

Advances in the Diagnosis and Treatment of Heart Failure with Preserved Ejection Fraction

射血分数保留的心力衰竭(HFpEF)已占据心力衰竭总人群的50%以上,且随着人口老龄化、肥胖症、糖尿病和高血压等患病率的上升而快速增长。由于HFpEF患者的高度异质性,病因多样,且缺乏特异性的早期症状和体征,其无创性诊断及治疗至今仍具有挑战性。本文就其近几年关于发病机制及诊疗的进展作一综述。

Heart failure with preserved ejection fraction (HFpEF) has accounted for more than 50% of the total heart failure population, and its prevalence is rapidly increasing with the aging, obesity, diabetes, and hypertension. Due to the high heterogeneity of HFpEF patients, diverse etiologies, and lack of specific early symptoms and signs, non-invasive diagnosis and treatment remain challenging. This article provides an overview of recent advances in the pathogenesis, diagnosis, and treatment of HFpEF.