系统性炎症指标在心力衰竭中的应用

Application of Systemic Inflammation Markers in Heart Failure

心力衰竭是多种心血管病的严重表现或中晚期阶段,是严重危及生命的临床综合征,具有发病率高、病死率高、住院率高、患者生活质量差以及医疗花费高等特点,努力减轻其造成的社会经济负担已成为全球公共卫生的主要优先事项。系统性炎症指标如中性粒细胞淋巴细胞比率(NLR)、淋巴细胞单核细胞比率(LMR)、血小板淋巴细胞比率(PLR)、全身性免疫炎症指数(SII)等已成为目前的研究热点,多项研究表明其与心血管疾病的发生发展有着紧密联系,同时易于计算和获取。现就系统性炎性指标在心力衰竭中的应用进行综述,加强对上述指标的监测有助于临床上预测心力衰竭的发生风险及预后。

Heart failure is a severe manifestation or middle to late stage of a variety of cardiovascular diseases. It is a serious life-threatening clinical syndrome characterized by high morbidity, high mortality, high hospitalization rate, poor quality of life of patients and high medical costs. Efforts to reduce the socio-economic burden caused by heart failure have become a major global public health priority. Systemic inflammation indicators such as neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR), and systemic immune inflammation index (SII) have become the focus of current research, and many studies have shown that they are closely related to the occurrence and development of cardiovascular diseases, and they are easy to calculate and obtain. This article reviews the application of systemic inflammatory indicators in heart failure. Strengthening the monitoring of these indicators is helpful to predict the risk and prognosis of heart failure in clinic.