老年人群系统性慢性炎症的评估与控制

Assessment and Control of Systemic Chronic Inflammation in the Elderly Population

系统性慢性炎症是体内持续存在的低度炎症反应,随着年龄增长机体在分子、细胞、组织水平发生多方面的免疫学改变,使老年人群的系统性炎症水平相对较高,进而引起多种老年性疾病的发生、发展。同时,老年性相关疾病的存在也是促进慢性炎症水平的重要因素。因此,控制系统性慢性炎症是延缓老年性疾病进程的重要途径,也是预防老年慢性疾病的重要策略。老年人群的系统性炎症水平的管理涉及炎症水平的评估与干预方案的设计等诸多方面,本文就相关领域的进展情况进行概述,期待给相关领域的研究者提供便捷的理解,也为后续研究提供一些思路。

Systemic chronic inflammation is a low-grade inflammatory response that persists in the body. The immunological changes occurring in molecular, cellular, and tissue events within the aged population lead to a significantly increased level of systemic inflammation, which contributes to the onset and progression of a variety of senile diseases. The presence of senile diseases itself plays a crucial role in promoting the level of chronic inflammation. Therefore, controlling systemic chronic inflammation is crucial for preventing initiation and slowing progression of the senile diseases. There are multiple factors involved in managing systemic inflammation in older adults, such as assessing inflammation levels and creating intervention programs. This article gives an overview of advancements in related fields, aiming to offer a convenient understanding for researchers and inspire further research.