重复经颅磁刺激治疗脊髓小脑共济失调的研究进展

Progress of Repetitive Transcranial Magnetic Stimulation in the Treatment of Spinocerebellar Ataxia

脊髓小脑共济失调(spinocerebellar ataxia, SCA)是一种常染色体显性遗传疾病,以进行性平衡和协调能力障碍为主要特征,常表现为步态共济失调、运动障碍和构音障碍,严重影响患者的生活质量,增加患者的心理和经济负担。一直以来,SCA缺乏有效的治疗方法,近年来应用重复经颅磁刺激(Repetitive Transcranial Magnetic Stimulation, rTMS)治疗SCA取得了一定疗效,本文对重复经颅磁刺激治疗脊髓小脑共济失调的研究进展综述,以期提高对脊髓小脑共济失调新治疗方式的认识。

Spinocerebellar ataxia (SCA) is an autosomal dominant genetic disease, which is mainly characterized by progressive balance and coordination disorders, often manifested as gait ataxia, movement disorders and dysarthria, which seriously affects the quality of life of patients and increases their psychological and economic burden. In recent years, repetitive transcranial magnetic stimulation (rTMS) has been used to treat SCA, and this article reviews the research progress of repetitive transcranial magnetic stimulation in the treatment of spinocerebellar ataxia, in order to improve the understanding of new treatment modalities for spinocerebellar ataxia.