局晚期头颈鳞癌辅助化疗的研究现状

Research Status of Adjuvant Chemotherapy for Advanced Head and Neck Squamous Cell Carcinoma

局晚期头颈部鳞癌(head and neck squamous cell carcinoma)是常见的恶性肿瘤,有超过一半的患者被发现时处于局部晚期,生存率不高,主要治疗手段以手术及放疗为主,但全身化疗也越来越多地与放疗和手术相结合,比如辅助化疗、诱导化疗及同步化疗。本文就局部晚期头颈部鳞癌辅助化疗的研究现状做一综述,旨在为临床工作中是否应对局晚期头颈部鳞癌患者行辅助化疗提供参考。

Advanced head and neck squamous cell carcinoma is a common malignant tumor, more than half of the patients are found in the local advanced stage, the survival rate is not high, the main treatment methods are mainly surgery and radiotherapy, but systemic chemotherapy is also increasingly combined with radiotherapy and surgery, such as adjuvant chemotherapy, induction chemotherapy and synchronous chemotherapy. This article reviews the current research status of adjuvant chemotherapy for locally advanced head and neck squamous cell carcinoma, aiming to provide reference for whether adjuvant chemotherapy should be performed in clinical work for patients with locally advanced head and neck squamous cell carcinoma.