基于脾–线粒体相关性探析“脾主运化”理论治疗慢性心力衰竭

Exploring “Spleen Governs Transportation and Transformation” Theory in Treating Chronic Heart Failure Based on Association between Spleen and Mitochondria

慢性心力衰竭是多种心血管疾病终末期,其发展过程中的关键因素之一是线粒体能量代谢的不稳定状态。线粒体主要承担着产生能量以维持机体正常生命活动的职责,这与负责消化吸收水谷精微并将其转化成人体所需营养物质的“脾”有异曲同工之妙。中医学认为,心气亏虚是慢性心力衰竭发生的关键病机,而心气盛衰多依赖于脾主运化功能的强弱。因此,本文基于脾与线粒体相关性,对“脾主运化”理论治疗慢性心力衰竭进行深入探讨,以期为慢性心力衰竭的防治提供更多的思考方向。

Chronic heart failure is the end-stage of a variety of cardiovascular diseases, and one of the key factors in its development is the unstable state of mitochondrial energy metabolism. Mitochondria mainly bear the responsibility of generating energy to maintain normal life activities in the body, which is similar to the “spleen” responsible for digesting and absorbing food and converting it into the necessary nutrients for the human body. Traditional Chinese medicine believes that deficiency of heart qi is the key pathogenesis of chronic heart failure, and the rise and fall of heart qi mostly depend on the strength of the spleen’s main transportation and transformation function. Therefore, based on the correlation between the spleen and mitochondria, this article delves into the treatment of chronic heart failure with the theory of “spleen governs transportation and transformation”, in order to provide more thinking directions for the prevention and treatment of chronic heart failure.