硼中子俘获治疗应用及展望

Boron Neutron Capture Therapy Application and Prospects

癌症的发病率和死亡率一直保持在相对比较高的水平,且有逐年上升的趋势,而现在精准放疗的概念逐渐引进现代医疗,所以一种新的癌症治疗方法——硼中子俘获疗法(boron neutron capture therapy, BNCT)值得进一步发展,尽管在该方法的研究中存在诸多问题,但BNCT的发展和临床应用前景十分广阔,并且符合现代医疗的观点。本文章介绍了新技术BNCT的原理及其发展,目前可用的硼递体的特点,以及BNCT的临床应用。

The incidence and mortality of cancer have been maintained at a relatively high level and have been increasing year by year, and now the concept of precision radiotherapy is gradually introduced into modern medicine, so a new cancer treatment method, boron neutron capture therapy (BNCT), is worthy of further development, although there are many problems in the research of this method, the development and clinical application of BNCT are very promising, and it is in line with the perspective of modern medicine. This article describes the principles and development of the new technology BNCT, the characteristics of currently available boron transmitters, and the clinical application of BNCT.