空间辐射对心血管系统的影响

The Impact of Space Radiation on the Cardiovascular System

太空飞行过程中,空间辐射引发心血管及循环系统调控改变,是太空飞行对航天员健康的重要威胁。本文旨在介绍空间辐射的来源和种类、心血管系统损害及辐射防护方法,并重点关注心肌细胞、内皮细胞、心肌成纤维细胞的适应性改变,尤其针对抗氧化剂、抑制剂等生物防护措施进行了分析与讨论,以期为未来的太空飞行辐射防护提供新思路。

Space radiation induces changes in the regulation of cardiovascular and circulatory systems. During spaceflight, space radiation can potentially threaten astronaut health. This review summarizes the sources, types, cardiovascular system damage and radiation protection methods of space radiation, focusing on the adaptive changes induced by space radiation in the endothelial cells, cardiomyocytes and fibroblasts. In particular, the biological protection measures such as antioxidants and inhibitors are analyzed and discussed, in order to provide new ideas for radiation protection in future spaceflight.