2型糖尿病骨质疏松的治疗研究

A Study of the Treatment of Osteoporosis in Type 2 Diabetes Mellitus

目前,2型糖尿病(T2DM)、骨质疏松症都是常见的慢性疾病,随着年龄的增加,发病率也会不断升高。T2DM与骨质疏松之间关系密切,T2DM会导致骨质疏松的风险增加,需尽早干预。本文旨在回顾T2DM患者骨质疏松和骨折风险的相关研究,分别讨论降糖药物对骨代谢及抗骨质疏松药物对血糖的影响,以及对骨质疏松的现有治疗方案加以总结,以期为该病的治疗及相关研究提供参考,并为最佳治疗提供个性化指导。

Currently, type 2 diabetes mellitus (T2DM) and osteoporosis are common chronic diseases with increasing prevalence with age. There is a close relationship between T2DM and osteoporosis, and T2DM leads to an increased risk of osteoporosis and requires early intervention. The purpose of this article is to review the studies related to osteoporosis and fracture risk in patients with T2DM, to discuss the effects of glucose-lowering drugs on bone metabolism and anti-osteoporosis drugs on blood glucose, respectively, as well as to summarize the existing treatment options for osteoporosis, with the aim of providing a reference to the treatment of this disease and related studies, and to provide personalized guidance for the optimal treatment.