MRI影像组学在乳腺癌中的应用进展

Research Progress of Multiparametric MRI Radiomics in Breast Cancer

乳腺癌是女性最常见的恶性肿瘤之一。磁共振成像因其良好的软组织分辨率、无辐射、可重复性等特点现已成为乳腺癌常用检查方法。影像组学技术通过高通量地提取人眼无法观察到的影像组学特征来反映肿瘤内异性,具有可重复性、无创性及客观性等特点,现已广泛应用于乳腺癌诊断、淋巴结转移评估及新辅助疗效评估等方面。本文就基于MRI影像组学技术在乳腺癌诊疗中的研究进展予以综述,并探讨当前存在的局限性及挑战,以期为临床个体化精准医疗提供新思路。

Breast cancer is one of the most common malignant tumours in women. Magnetic resonance imaging has now become a commonly used screening method for breast cancer due to its good soft tissue resolution, no radiation and reproducibility. Imaging histology technology reflects the internal heterogeneity of the tumour through high-throughput extraction of imaging histological features that cannot be observed by the human eye, which is reproducible, non-invasive and objective, and is now widely used in the diagnosis of breast cancer, the assessment of lymph node metastasis, and the evaluation of neoadjuvant therapeutic efficacy. In this paper, we review the research progress of MRI-based imaging histology in breast cancer diagnosis and treatment, and discuss the current limitations and challenges, with a view to providing new ideas for clinical individualised precision medicine.