下肢深静脉血栓形成后综合征的诊疗进展

Progress in Diagnosis and Treatment of Syndrome after Deep Vein Thrombosis in the Lower Limbs

深静脉血栓形成后综合征(PTS)是深静脉血栓形成(DVT)一个重要的慢性并发症。目前研究的焦点都集中下肢PTS的高危因素及如何预防和治疗上,首次患有下肢DVT的患者在两年内发展成下肢PTS的比例高达20%~50%,下肢PTS常表现为受累下肢的慢性酸疼、肿胀、疲乏等为表现,其中严重的PTS占5%~10%,主要表现为静脉性跛行及溃疡。就下肢PTS最新的病理生理、高危因素、诊断及预防、治疗进展等方面提供参考。然而就目前关于PTS的诊断与治疗尚无统一的共识,值得我们关注。

Post-thrombotic syndrome (PTS) is an important chronic complication of deep vein thrombosis (DVT). The current focus of research is on the high-risk factors for lower limb PTS and how to prevent and treat it. Within two years, the proportion of patients with lower limb DVT developing into lower limb PTS can reach as high as 20%~50%. Lower limb PTS is often characterized by chronic pain, swelling, and fatigue in the affected limb, with severe cases accounting for 5%~10% and manifesting as venous claudication and ulcers. This paper provides a comprehensive review of the latest pathological and physiological aspects, high-risk factors, diagnosis, prevention, and treatment advances in lower limb PTS. However, currently there is no unified consensus on the diagnosis and treatment of PTS, which warrants our attention.