鼻腔恶性黑色素瘤术后复发1例报道及文献复习

Case Report and Literature Review of a Recurrence of Nasal Malignant Melanoma after Surgery

鼻腔及鼻窦恶性黑色素瘤来源于鼻腔黏膜的树状突黑色素细胞,其发生率占头颈部恶性肿瘤的2%左右。该类肿瘤因恶性程度高,易复发和转移,由此预后较差。且大多数共识中未提及鼻腔黑色素瘤术后复发的治疗方案,所以如何选择适当的治疗方法,最大限度提高鼻腔及鼻窦恶性黑色素瘤患者的生存期及生活质量一直是临床的难点。本例为一例鼻腔黏膜恶性黑色素瘤术后复发的患者,结合文献复习,对该疾病初诊疗进行回顾分析,以期为此类患者的临床诊疗提供参考。Nasal and paranasal malignant melanomas originate from dendritic melanocytes in the nasal mucosa, accounting for approximately 2% of malignant tumors in the head and neck region. These tumors are highly malignant, prone to recurrence and metastasis, resulting in poor prognosis. Current consensus guidelines often lack detailed treatment protocols for recurrent nasal melanoma post-surgery. Thus, selecting the most appropriate treatment to maximize survival and quality of life for patients with nasal and paranasal malignant melanoma remains a clinical challenge. This report details a case of recurrent nasal mucosal malignant melanoma following surgery. A review of the literature is conducted to analyze initial diagnosis and treatment strategies, providing clinical insights for managing similar cases.