MHR与慢性肾脏病心血管并发症的相关研究进展

Research Progress on MHR and Cardiovascular Complications of Chronic Kidney Disease

近年来,慢性肾脏病的患病人数逐渐升高,心血管疾病是慢性肾脏病最常见并发症及首要死亡原因,给人类健康带来了很大威胁。除了高血脂、糖尿病等传统危险因素外,贫血、钙磷代谢失调、炎症等对心血管意外的发生也有一定的影响。单核细胞数与高密度脂蛋白胆固醇比值(MHR)是反映炎症和氧化应激的一项新指标。本文将对MHR对慢性肾病心血管并发症的相关研究进行综述。In recent years, the number of people with chronic kidney disease (CKD) has gradually increased, and cardiovascular disease is the most common complication and leading cause of death from CKD, which poses a great threat to human health. In addition to traditional risk factors such as hyperlipidemia, diabetes, etc., anemia, calcium and phosphorus metabolism disorders, and inflammation also have a certain impact on the occurrence of cardiovascular accidents. The ratio of monocyte count to HDL cholesterol (MHR) is a novel indicator of response to inflammation and oxidative stress. This article will review the relevant studies on the effects of MHR on cardiovascular complications of chronic kidney disease.