心血管疾病常用中药注射液研究概况

Survey of Commonly-Used Traditional Chinese Medicine Injections for Cardiovascular Disease

本文通过查阅中国知网(CNKI)、PubMed及相关参考书目,对目前心血管疾病常用中药注射液及其涉及中药有效组分的相关文献进行归纳及分析。文章所载中药注射液有川芎嗪注射液、丹参酮IIA磺酸钠注射液等5种中药注射液,其主要成分多数源自单味中药;中药中有效组分被提取作为中药注射液主要成分是趋势,占比80%;以上中药注射液不仅仅适用于某个中医证型,在相关心血管疾病中多有应用;涉及中药有丹参、川芎等,有效组分类型有皂苷和黄酮类等;多具有保护缺血再灌注损伤、抗炎、抗氧化、抗血栓形成等药理作用。本文为防治心血管疾病提供依据。China Knowledge Network (CNKI), PubMed and relevant bibliographies were consulted to summarize and analyze the current commonly-used traditional Chinese medicine injections (TCMIs) for cardiovascular diseases and their related literature involving the active components of traditional Chinese medicines. In this paper, there are 5 types of TCMIs, including ligustrazine injection, tanshinone IIA sodium sulfonate injection etc. The majority are derived from single-flavored Chinese medicines. It is a trend that the effective components of Chinese medicines are extracted to be the main ingredients of Chinese medicine injections, which accounts for 80% of the total. The above Chinese medicine injections are not only applicable to a certain TCM type, but also to the relevant cardiovascular diseases, in which they can be used in a variety of ways. Involving Chinese medicines such as Salvia miltiorrhiza and Rhizoma Ligustici Chuanxiong, etc., and the types of active components include saponins and flavonoids, etc. Most of them have the pharmacological effects of protection against ischemia-reperfusion injury, anti-inflammation, antioxidation and anti-thrombosis. This article can provide the basis of prevention and treatment of cardiovascular diseases.