棕色脂肪组织和心血管疾病的关系

Relationship between Brown Adipose Tissue and Cardiovascular Disease

在人体中存在一种特殊的脂肪组织,称为棕色脂肪组织,成人体内主要分布于锁骨上区和颈部,其具有产热、调节代谢、分泌等功能,与II型糖尿病、血脂异常等多种代谢疾病密切相关。最新研究显示,棕色脂肪组织具有心血管保护作用。本文将从棕色脂肪组织出发,对其与动脉粥样硬化、心力衰竭、高血压、肺动脉高压之间的潜在联系展开综述。Brown adipose tissue (BAT) is a distinct type of fat tissue found predominantly in the supraclavicular area and neck of adult humans. It is characterized by its ability to generate heat, regulate metabolism, and secrete various factors, and it is closely related to various metabolic diseases including type 2 diabetes and dyslipidemia. Emerging research indicates that BAT may offer protective effects against cardiovascular diseases. In this review, we will discuss the characteristics of BAT and its potential connections with atherosclerosis, heart failure, hypertension, and pulmonary arterial hypertension.