基于肠道菌群探讨中医药治疗动脉粥样硬化的研究进展

Exploring the Research Progress of Traditional Chinese Medicine in the Treatment of Atherosclerosis Based on Intestinal Flora

动脉粥样硬化作为心血管疾病的主要病理基础,其发病机制复杂且多样,涉及脂质代谢异常、炎症反应、遗传及血管内皮损伤等多个方面。近年来,肠道菌群作为人体内部微生态系统的重要组成部分,其在动脉粥样硬化发生发展中的作用逐渐受到广泛关注。中医药,作为传统医学的瑰宝,凭借其独特的理论体系和治疗手段,在调节肠道菌群、防治动脉粥样硬化方面展现出了显著的潜力与优势。本文旨在全面综述中医药对肠道菌群与动脉粥样硬化关系的研究进展及治疗现状,探讨其潜在机制与临床应用前景。Atherosclerosis, as the main pathological basis of cardiovascular disease, has a complex and diverse pathogenesis involving abnormal lipid metabolism, inflammatory response, genetics and endothelial damage. In recent years, the role of intestinal flora in the development of atherosclerosis, as an important part of the internal microecosystem of the human body, has received widespread attention. Traditional Chinese medicine (TCM), as a treasure of traditional medicine, has shown remarkable potential and advantages in regulating intestinal flora and preventing atherosclerosis by virtue of its unique theoretical system and therapeutic means. The aim of this paper is to comprehensively review the research progress and treatment status of TCM on the relationship between intestinal flora and atherosclerosis, and to explore its potential mechanism and clinical application prospect.