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睡眠剥夺对抑郁的影响及其作用机制

Effects of Sleep Deprivation on Depression and Mechanisms of Action
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摘要 作为治疗抑郁症的疗法之一,睡眠剥夺尚未在临床实践中得到广泛应用,目前较多地存在于实验室研究中。但相较于其他疗法,睡眠剥夺疗法的优点在于其快速抗抑郁的作用,而且没有明显的副作用和禁忌症,这对开发新的抑郁症疗法具有启发作用。研究表明,睡眠剥夺的抗抑郁作用与个体的睡眠节律、神经网络的改变和神经递质的改变等相关。未来的研究需要更多地关注睡眠剥夺疗法的作用机制,尤其是其神经机制,为该疗法在临床实践中的应用提供支持。 As one of the therapies for depression, sleep deprivation has not been widely applied in clinical practice and is currently more present in laboratory studies. However, the advantages of sleep deprivation therapy over other therapies are its rapid antidepressant effect and the absence of significant side effects and contraindications, which can be an inspiration for the development of new therapies for depression. Studies have shown that the antidepressant effects of sleep depri-vation are associated with individual sleep rhythms, alterations in neural networks, and changes in neurotransmitters. Future research needs to pay more attention to the mechanisms of action of sleep deprivation therapy, especially its neural mechanisms, to support the application of this therapy in clinical practice.
作者 贾燕
机构地区 西南大学
出处 《社会科学前沿》 2023年第3期1163-1167,共5页 Advances in Social Sciences
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