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ISG56/IFIT1家族研究进展

Research Progress of ISG56/IFIT1 Family
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摘要 ISG56/IFIT1家族是干扰素刺激基因的成员,其被病毒或干扰素调控,在抗病毒免疫以及干扰素信号通路的调控中发挥了多种生物学功能。本文对ISG56家族基因结构、蛋白特点、调控通路、表达特点和生物学功能等最新研究进展进行总结和归纳。 ISG56/IFIIT1 family are the members of IFN-stimulated genes. They are regulated by virus or IFN, and they perform a variety of biological functions in antiviral immunity and the regulation of interferon signaling pathway. In this paper, the recent progress of ISG56 family, including gene structure, protein characteristics, regulatory pathway, expression characteristics and biological functions was summarized.
出处 《生物过程》 2017年第2期9-13,共5页 Bioprocess
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  • 1Chebath J, Merlin G, Metz R, Benech P, Revel M. Interferon- induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNA. Nucleic Acids Res 1983; 11:1213-1226.
  • 2Wathelet M, Moutschen S, Defilippi P, et al. Molecular clon- ing, full-length sequence and preliminary characterization of a 56-kDa protein induced by human interferons. Eur J Bioehem 1986; 155:11-17.
  • 3Kessler DS, Levy DE, Darnell JE Jr. Two interferon-induced nuclear factors bind a single promoter element in interferon- stimulated genes. Proc Natl Acad Sci USA 1988; 85:8521- 8525.
  • 4Yu M, Tong JH, Mao M, et al. Cloning of a gene (RIG-G) associated with retinoic acid-induced differentiation of acute promyelocytic leukemia cells and representing a new member of a family of interferon-stimulated genes. Proc Natl Acad Sci USA 1997; 94:7406-7411.
  • 5de Veer MJ, Sim H, Whisstock JC, Devenish RJ, Ralph SJ. IFI60/ISG60/IFIT4, a new member of the human IFI54/ IFIT2 family of interferon-stimulated genes. Genomics 1998; 54:267-277.
  • 6Yan N, Chert ZJ. Intrinsic antiviral immunity. Nat ImmunoI 2012; 13:214-222.
  • 7Sen GC, Sarkar SN. The interferon-stimulated genes: targets of direct signaling by interferons, double-stranded RNA, and viruses. Curr Top Microbiol lmmunol2007; 316:233-250.
  • 8Fensterl V, Sen GC. The ISG56/IFIT1 gene family. J Interferon Cvtokine Res 2011; 31:71-78.
  • 9Fensterl V, Wetzel JL, Ramachandran S, et al. Interferon- induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis. PLoS Pathog 2012; 8:e 1002712.
  • 10Guo J, Sen GC. Characterization of the interaction between the interferon-induced protein P56 and the Int6 protein en- coded by a locus of insertion of the mouse mammary tumor virus. J Virol2000; 74:1892-1899.

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