药用植物中香豆素类化合物的分析方法研究进展

Progress on Analytical Methods for Coumarins in Medicinal Plants

传统中药蛇床子、秦皮、白芷等含有丰富的香豆素。香豆素类化合物具有抗HIV、抗肿瘤、抗炎、抗氧化、抗菌等多方面的生物学活性,已经作为中药质量控制的一类重要指标成分,因此香豆素类化合物的分析检测具有重要意义。本文就药用植物中香豆素的分析方法的研究现状进行了综述,比较了各种分析方法的特点,并对其发展趋势和应用前景进行了展望。

Coumarins compounds are one kind of active ingredient in Chinese traditional medicine, such as Fructus Cnidii, Fraxini Cortex, Angelica dahurica etc. Coumarins have anti-HIV, anti-tumor, an-ti-inflammatory, anti-oxidation, antibacterial and other biological activities, which have acted as important index for quality control of Chinese material medica. Therefore, it is important to detect the amount of coumarins in medicinal plants. Herein, the progress on analytical methods for cou-marins in medicinal plants was summarized and reviewed. The advantages and disadvantages of various analytical methods were discussed and the further research orientations were also pro-spected in this paper.