蛋白质组学研究方法在蚕丝学中的应用

Application of the Technology about Proteomics in Sericulture Research

家蚕既是具有重要经济价值的绢丝昆虫,又是现代生命科学研究的模式生物。近年来,随着蛋白质组学研究技术的飞速发展,有关家蚕性腺、丝腺、血液、中肠、触角等重要组织器官蛋白质组学的研究取得了很大进展,为揭示家蚕重要性状的形成机制、生殖发育调控、组织器官功能、天然免疫等方面提供了丰富的信息。文章对此作了简要的综述,并结合基因组学、生物信息学的研究技术,讨论了家蚕蛋白质组学今后的发展趋势及其应用前景。

Silkworm (Bombyx mori) is not only an important economic insect, but also a model organism in modern life science research. In recent years, with the rapid progress in proteomics research technology, proteomic research of essential organs such as silkworm gonad, silk gland, midgut, hemolymph, antennae and other important organs has made great progress. An abundant infor-mation resource is provided by the results of these researches for revealing the important char-acters of silkworm formation mechanism, reproductive and developmental regulation, tissues and organs function, innate immunity, et al. A brief review is given in this paper for discussing the future development trend and application prospect of silkworm proteomics in combination with genomics and bioinformatics.