肠道菌群与痛风的相关性研究进展

Research Progress on the Relationship between Gut Microbiota and Gout

痛风作为一种代谢性疾病,严重地威胁人类健康。肠道菌群作为人类的第二基因组与人类疾病之间的相互关系逐渐被发现,痛风与肠道菌群的相关性也倍受研究者的关注。本文拟从痛风患者肠道菌群特点、肠道菌群及代谢产物与痛风的关系等多个方面探讨痛风的发病机制,为痛风的诊断和有效治疗以及预防提供依据。

As a metabolic disease, gout threatens human health seriously. The gut microbiota, as the second human genome, has gradually been found to be related to human diseases. The correlation between gout and gut microbiota has also attracted much attention from researchers. This article intends to explore the pathogenesis of gout from the characteristics of gout patients’ intestinal flora, the relationship between gut microbiota, metabolites and gout, and provide a basis for the diagnosis, effective treatment and prevention of gout.