N,N-二烷基乙醇胺的合成工艺研究进展

Overview on the Progress of Synthesis of N,N-Dialkylethanolamine

N,N-二烷基乙醇胺是一种重要的精细化工中间体,在纺织、医药、农用化学品等方面具有广泛的应用。本文根据起始原料不同将其合成路线分为两大类,即:仲胺的羟乙基化和乙醇胺的N-烷基化,并较系统地归纳总结了各不同合成路线的特点,对N,N-二烷基乙醇胺的合成路线优化与生产工艺改进具有指导意义。

N,N-dialkylethanolamine is an important intermediate in fine chemical industries, especially in textile, pharmaceuticals, and agrochemicals. According to different starting material, the synthetic route can be divided into two categories: Hydroxyethylation of secondary amines and N-alkylation of ethanolamine. The characteristic features of each route are summarized in this paper systematically. And it is important for the optimization and development of synthetic process of N,N- dialkylethanolamine.