摘要
龙葵素是一种重要的糖苷生物碱,具有多种生物学作用,能对多种疾病起到防治的作用,其中包括抗肿瘤作用。龙葵素在抗肿瘤作用从细胞和分子途径诱导细胞的凋亡和自噬,使癌细胞的迁移、浸润、血管发生一起转移能力受到抑制。因此,本文就龙葵素对各种癌细胞的抑制作用及其作用机制进行了综述。
Solanine is an important glycoalkaloid, with a variety of biological effects. It plays a role in pre-vention and treatment of many diseases, including its anti-tumor effect. Solanine exhibits its an-ti-tumor effect through regulation several cellular and molecular pathways which induce cell apoptosis and autophagy, and inhibit cancer cells’ migration, invasion, angiogenesis and metastasis. Therefore, anti-cancer effects of solanine and its mechanism are reviewed in this article.
出处
《食品与营养科学》
2016年第2期26-30,共5页
Hans Journal of Food and Nutrition Science
基金
“国家自然科学基金”(31371683)
“作物种质创新与资源利用重点实验室科学基金项目”(12KFXM02)。