叶黄素生物利用与脂类相关性研究进展

The Advance of Research on the Role of Lipids on the Biological Utilization of Lutein

叶黄素是一种脂溶性类胡萝卜素,广泛存在于绿叶蔬菜、鸡蛋等食物中。其在人体中的整个生物利用过程,包括消化、吸收、运输、代谢等过程均与脂类有密切关系。膳食叶黄素的消化吸收需要多种脂类参与,膳食脂肪的质与量均影响其生物利用度。在循环中,叶黄素需要与载脂蛋白一起在血液中运输。其在不同载脂蛋白中的分配比例有很大的差异,血浆胆固醇种类和含量均可能影响其转运效率。此外,脂类相关受体,基因和激素在叶黄素的组织利用过程中发挥重要作用。本文通过综述脂类在叶黄素人体生物利用中的作用,拟为叶黄素应用于人群干预提供有益信息。

Lutein is a fat-soluble carotenoid present in various kinds of food, such as green leafy vegetables and eggs. The utilization of lutein in human body, including digestion, absorption, transport and metabolism, is associated with lipids. The digestion and absorption of lutein from food require the participation of fat. Both the amount and quality of dietary fat could influence the bioavailability of lutein. In circulation, lutein is transported in serum with lipoprotein. The percentage distribution of lutein varies among different lipoproteins, and serum cholesterol level could influence its transport efficiency. Furthermore, the lipid receptors, lipid-related hormone and gene play an important role on the tissue utilization of lutein. In this article, we reviewed the roles of lipids in the biological utilization of lutein in human body and trying to provide some beneficial information on the dietary supplement of luteinin population.