植物乳杆菌R-15对高脂饮食下小鼠体质量及血脂的影响研究

The Effect of Lactobacillus plantarum R-15 on Body Weight and Blood Lipids of Mice with High-Fat Diet

为研究植物乳杆菌R-15对高脂饮食小鼠体质量及血脂的影响,将40只成年洁净级雄性昆明小鼠随机分为普通组、高脂组、R-15-7d组和R-15-35d组等四组,其中普通组施喂基础饲料,高脂组施喂高脂饲料,R-15-7d组和R-15-35d组(施喂高脂饲料和R-15菌悬液),检测小鼠体质量、脏器指数、血脂和血糖。结果显示:R-15-35d组在采食量相近的情况下,小鼠体质量增长最为缓慢(P 0.05),但可改善高脂饮食造成的脾脏指数增加(P 0.05)。

In order to study the effect of Lactobacillus plantarum R-15 on body weight and serum lipids of mice fed with high-fat, forty clean grade adult male Kunming mice were equivalently divided into four groups randomly, named normal group, high-fat group, R-15-7d group, and R-15-35d group individually. Among of them, mice of normal group were fed with basic feed, high-fat group were fed with high-fat feed, R-15-7d group and R-15-35d group were fed with high-fat feed and suspension of strain R-15. Finally, the body mass, organ index, blood lipids and glucose levels of mice in each group were measured. The results indicate that the body mass of mice in R-15-35d group increased most slowly under the con-dition of similar feed intake with other groups (P 0.05), but it could improve the increase of spleen index caused by high-fat diet (P 0.05).