摘要
目的:建立近红外光谱法快速检测银杏离心液中萜类内酯含量的方法。方法:利用近红外光谱仪对银杏离心液样品进行扫描,对其光谱进行预处理和波段选择,并结合偏最小二乘法(partial least squares, PLS)建立萜类内酯含量快速无损检测方法。结果:所建立的模型的决定系数R为0.9177,交叉验证均方根差值为0.0335,对验证集样品进行预测并统计分析,预测值与真实值之间无显著差异(P 】0.05)。结论:所建立的模型准确度高,适用于银杏离心液中萜类内酯含量的快速检测。
Objective: To establish a method for rapid determination of terpenoids in ginkgo centrifugal solu-tion by near infrared spectroscopy. Methods: NIR spectroscopy was used to scan the ginkgo centrif-ugal solution samples, and the spectra were pretreated and the bands were selected. A fast and non-destructive method for the determination of terpenoids was established by partial least squares (PLS) method. Results: The determination coefficients R of the established model were 0.9177, and the root mean square difference of cross-validation were 0.0335, respectively. There was no significant difference between the predicted value and the true value (P >0.05) after the prediction and statistical analysis of the validation set samples. Conclusion: The established model has high accuracy and is suitable for the rapid determination of terpenoids in ginkgo centrifugal solution.
出处
《药物化学》
2022年第1期39-45,共7页
Hans Journal of Medicinal Chemistry
