γ-丁内酯为原料合成戊二酸的CO₂光合成路径

CO₂ Photosynthetic Pathway for Synthesis of Glutaric Acid Using γ-Butyrolactone as a Raw Material

研究了以γ-丁内酯为原料合成戊二酸的新路径。γ-丁内酯先通过开环生成4-溴丁酸乙酯后,再在光照条件下,以CO2为碳源进行光催化的羰基化反应,最后再水解提纯得到戊二酸,其产率为35%。反应条件温和,且所需原料简单易得。

A new route to synthesize glutaric acid from γ-butyrolactone was studied. First, γ-butyrolactone is ring-opened to generate ethyl 4-bromobutyrate, and then photocatalytic carbonylation is carried out with CO2 as carbon source under light conditions, and finally glutaric acid is obtained by hy-drolysis and purification. The rate is 35%. The reaction conditions are mild, and the required raw materials are simple and easy to obtain.