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基于近红外光谱结合化学计量学的复方感冒灵颗粒浸膏中蒙花苷的检测研究

Detection of moisture in Radix Isatidis of Compound Ganmaoling Granules Based on Near Infrared Spectroscopy and Stoichiometry
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摘要 目的:本研究旨在建立近红外光谱法快速检测复方感冒灵颗粒浸膏中蒙花苷的方法。方法:通过近红外光谱仪对复方感冒灵颗粒浸膏进行扫描,通过对比不同预处理方法,使用SNV的预处理方法,结合PLS方法建立浸膏中蒙花苷定量模型。结果:相关系数R为0.9044,预测值和实际值之间没有明显的差异(P > 0.05)。结论所建立的模型准确度高,适用于复方感冒灵颗粒浸膏的蒙花苷的快速检测。本研究旨在建立近红外光谱法快速检测复方感冒灵颗粒浸膏中蒙花苷的方法。 Objective: The purpose of this study was to establish a method for rapid detection of monosine in compound ganmaoling granule extract by near infrared spectroscopy. Methods: The extract of Compound Ganmaoling Granules was scanned by near infrared spectrometer. By comparing different pretreatment methods, the pretreatment method of SNV was used, and the quantitative model of monosine in extract was established by PLS method. Results: The correlation coefficient R was 0.9044, and there was no significant difference between the predicted value and the actual value (P > 0.05). Conclusion: The established model has high accuracy and is suitable for the rapid detection of monosine in Compound Ganmaoling Granules. The purpose of this study was to establish a method for rapid detection of monosine in compound ganmaoling granule extract by near infrared spectroscopy.
出处 《药物化学》 2024年第1期9-14,共6页 Hans Journal of Medicinal Chemistry
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