干性老年黄斑变性的危险因素和预防研究现状

Advance in Risk Factors and Prevention of Dry Age-Related Macular Degeneration

年龄相关性黄斑变性(AMD)是重要的致盲眼病之一。临床上分为干性(萎缩型)和湿性(渗出型)两种类型,目前对于干性AMD仍无有效的治疗方法。本文从遗传、衰老、氧化应激及局部血流灌注等四个方面,对干性AMD的致病危险因素进行综述,从而为早期干预AMD提供新的思路和方法。

Age related macular degeneration (AMD) is one of the important causes of blindness. It can be di-vided into two types: dry (atrophy) and wet (exudative) AMD, there is still no effective treatment for dry AMD. In this article, we will review the research progress of dry AMD from the four risk factors of genetics, aging, oxidative stress and local blood perfusion. It will provide new ideas and methods for early intervention of dry AMD.