血液指标区分儿童急性阑尾炎严重程度的研究进展

Research Progress of Blood Indexes in Differentiating the Severity of Acute Appendicitis in Children

阑尾炎是儿童常见的腹部外科急症之一。在许多情况下,儿童阑尾炎的精确诊断仍具有挑战性。依据术中情况及术后组织病理学分型,急性阑尾炎被分为急性非复杂性阑尾炎(UA)和复杂性阑尾炎(CA)。阑尾切除一直以来是AA治疗的金标准,但目前有研究表明,部分UA患儿保守治疗效果良好,故在术前区分阑尾炎的不同严重程度十分必要。本研究基于血液指标,探索其在区分急性阑尾炎严重程度中的应用,结果表明:CRP、PCT、SAA、FIB、PLT、PLR、DD、PT、血钠、血清总胆红素,以及一些新的指标如DLAC、PTX3、FA、DNI在诊断CA中有意义。

Appendicitis is one of the most common abdominal surgical emergencies in children. Accurate diagnosis of appendicitis in children remains challenging in many cases. Acute appendicitis was divided into acute uncomplicated appendicitis (UA) and complicated appendicitis (CA) according to the intraoperative condition and postoperative histopathological classification. Appendectomy has always been the gold standard for AA treatment, but current studies have shown that conservative treatment in some children with UA has a good effect, so it is necessary to distinguish different severity of appendicitis before surgery. This study explores its application in differentiating the severity of acute appendicitis based on blood indicators. The results show that: CRP, PCT, SAA, FIB, PLT, PLR, DD, PT, serum sodium, serum total bilirubin, and some new Indicators such as DLAC, PTX3, FA, DNI are meaningful in diagnosing CA.