原甲藻属甲藻代谢产物研究进展

Research Progress on the Secondary Metabolites from Dinoflagellate Prorocentrum Spp.

原甲藻是形成海洋赤潮的生物种源之一,对海洋生态平衡和人类健康都有重要的影响。原甲藻的代谢产物丰富,主要有环状聚醚、大环内酯、生物碱等多种骨架类型的聚酮类化合物,以及甾醇等。本文总结了最近从原甲藻中得到的代谢产物的类型、结构以及生物活性,并对其研究前景进行展望,以期对原甲藻的进一步研究提供依据。

Prorocentrum spp. is one of the biological provenances for the formation of marine red tides. It has an important impact on the marine ecological balance and human health. The Prorocentrum genus is rich in metabolites, including polyketides with cyclic polyether, macrolide and alkaloid skeletons, steroids and some. In this paper, the types, structures and bioactivities of metabolites recently obtained from Prorocentrum spp. were summarized, and the prospect of its research was also discussed in order to provide the basis for further study of this genus.