热惊及热惊附加症相关基因的研究进展

Gene Research Progress of Febrile Seizures and Febrile Seizure Plus

热性惊厥(febrile seizures FS)是一种儿童时期的常见病。它是指发生在婴幼儿时期伴随有发热的惊厥发作,并排除既往曾有无热惊厥史患儿、中枢神经系统感染患儿等。热性惊厥附加症(febrile seizure plus FS+)是一个新提出的热性惊厥类型,国际抗癫痫联盟(International League Against Epilepsy ILAE)已经把热性惊厥附加症作为一种癫痫综合征收录。近年来随着精准医疗理念的提出,疾病的基因研究变得更加重要,此文就以上两种疾病相关基因的研究进展进行简单的综述。

Febrile seizures (FS) is a common disease in childhood. It’s defined as seizures in association with a febrile illness, occurring in children older than 1 month and without prior afebrile seizures or in the absence of a central nervous system infection. Febrile Seizure Plus (FS+) is a new type syndrome of Febrile seizures. The International League against Epilepsy ILAE regard it as a kind of epilepsy syndrome. Recently, gene research plays a important role with the Precision Medical appearing. So we conclude the relevant gene research of FS and FS+.