重症社区获得性肺炎病原学及检测技术研究进展

Research Progress on Etiology and Detection Technology of Severe Community Pneumonia

重症社区获得性肺炎(SCAP)是社区获得性肺炎(CAP)中最威胁生命的一种,其特征是高发病率和死亡率。在临床实践中,CAP的微生物病因往往不清楚,不同的研究有不同的报道结果。随着时间的发展,病原微生物谱也发生了很大的变化。然而,在SCAP中,确定病因是调整抗生素治疗的基石。近年来随着检测技术的进展,越来越多的病原微生物被检出,为指导临床治疗提供了极大的帮助。本片综述主要对近几年来,SCAP病原学变化及检测技术进展进行相应的描述。

Severe community pneumonia (SCAP) is one of the most life-threatening types of community pneumonia (CAP), which is characterized by high morbidity and mortality. In clinical practice, the microbial etiology of CAP is often unclear, and different studies have different reported results. The spectrum of pathogenic microorganisms also changed greatly with time. However, determining the etiology in SCAP is the cornerstone of antibiotic treatment. In recent years, with the development of detection technology, more and more pathogenic microorganisms have been detected, which provides great help for guiding clinical treatment. This review mainly describes the pathogen changes and detection technology progress of SCAP in recent years.