路易斯酸对苯乙酮和四丁基三溴化铵反应的影响

Effects of Lewis Acids on the Reaction of Acetophenone and Tetrabutylammonium Tribromide

本文考察了苯乙酮和四丁基三溴化铵(TBABr3)的溴代反应中路易斯酸对反应速率的影响。在所研究的路易斯酸的范围内,ZnCl2、AlCl3和FeCl3能加速反应的进行,但是FeCl2和NiCl2抑制了溴代反应。从结果来看,FeCl3不仅能显著缩短反应时间,同时收率也有所提高。

We investigate the effects of some Lewis acids (ZnCl2, AlCl3, FeCl3, FeCl2, and NiCl2) on the α-bro- mination rate of acetophenone with tetrabutylammonium tribromide. It is found that some Lewis acids, such as ZnCl2, AlCl3, and FeCl3, can accelerate bromination of acetophenone, but others such as FeCl2 and NiCl2 inhibited the bromination. Among the catalytic Lewis acids, FeCl3 could significantly accelerate the reaction without loss of the yield.