1,1-双(6-甲氧基-4'-(萘-1-基)-[1,1'-联苯]-3-基)丙-2-炔-1-醇的合成与分析

Synthesis and Analysis of 1,1-Bis(6-Methoxy-4'-(Naphthalen-1-Yl)-[1,1'-Biphenyl]-3-Yl)Prop-2-Yn-1-Ol

丙炔醇是一类重要的中间产物,其在医药和材料领域都有很广泛的应用。本文以4,4’-二甲氧基二苯甲酮为原料通过Suzuki等反应合成1,1-双(6-甲氧基-4'-(萘-1-基)-[1,1'-联苯]-3-基)丙-2-炔-1-醇,并通过核磁共振氢谱和核磁共振碳谱手段对中间产物和最终产物进行表征。

Propynol is an important intermediate and organic chemical raw material. It has a very wide range of applications in the field of medicine and materials. 1,1-bis(6-methoxy-4'-(naph-thalen-1- yl)-[1,1'-biphenyl]-3-yl)prop-2-yn-1-ol was efficiently synthesized by bis(4-methoxyphenyl)me- thanone. The product was well characterized by 1H NMR and13C NMR.