聚苯乙烯负载二芳基脯氨醇的合成及其催化查尔酮的对映选择性环氧化反应研究

Synthesis of Polystyrene Supported Diarylprolinol and Its Catalytic Enantioselective Epoxidation of Chalcone

合成了聚苯乙烯负载的二芳基脯氨醇,并在TBHP氧化条件下将其应用于催化查尔酮的对映选择性环氧化反应,以中等的产率(最高达70%)和较好的对映选择性(最高达79% ee)合成了系列手性环氧化合物。催化剂经过两次循环利用,其催化性能基本保持不变。

Polystyrene supported diarylprolinols were synthesized and applied them to catalytic enantiose-lective epoxidation of chalcones when TBHP as oxidant.A series of chiral epoxides was obtained with moderate yield(up to 69.7%yield)and good enantioselectivity(up to 78.7%ee).After two catalytic cycles,the performance of the catalyst basically remained.