不对称有机催化反应的国内研究进展

Progress of Domestic Research of Asymmetric Organic Catalysis

目前,手性分子的合成已经是化学科学研究的一个核心领域。在众多已报道的合成方法中,不对称有机催化已成为获得手性化合物的最直接有效的方法之一。在过去的几十年里,不对称催化取得了重大进展,化学家们也设计并合成了各种不同类型的有机小分子催化剂。本文主要从不对称有机催化方面综述了近年来国内化学家在该方向的研究进展。在此,我们并未对所有文献进行罗列而是选取了有代表性的例子,以突出在这一领域取得的重要进展。

At present, the synthesis of chiral molecules has been a core research area in chemical science and technology. Among the plethora of reported synthetic methods, asymmetric organic catalysis has emerged as one of the most efficient and direct ways to obtain optically pure chiral compounds. Over the past several decades, significant progress has been achieved in asymmetric organic catalysis, and various types of organic small molecule catalysts have been carefully designed and synthesized by chemists. This article mainly reviews the recent progress of asymmetric catalysis made by Chinese chemists from asymmetric organic catalysis. Here, this review does not intend to be comprehensive, but only representative examples are selected to highlight the important progress made in this field.