PCT对脓毒症的诊断及预后价值探讨

Discussion on the Diagnostic and Prognostic Value of PCT in Sepsis

目的:探讨降钙素原(Procalcitonin, PCT)对脓毒症的诊断及预后价值。方法:收集2020年9月~2021年9月于大理大学第一附属医院就诊的40例健康体检者、40例入住ICU病房非脓毒症患者及60例脓毒症患者的相关资料,随后根据脓毒症患者预后分成生存组(n = 36)及死亡组(n = 24),比较不同组别中的PCT水。结果:脓毒症组PCT水平显著高于病例对照组及健康对照组(P < 0.05),脓毒症死亡组PCT水平显著高于生存组(P < 0.05);受试者工作特征(Receiver Operating Characteristic Curve, ROC)曲线分析表明PCT对脓毒症的诊断性能及预后判断价值较高。结论:PCT对脓毒症有较好的诊断效能,并对其预后有较高的预测价值,为临床的进一步应用奠定了基础。

Objective: To investigate the diagnostic and prognostic value of Procalcitonin (PCT) in sepsis. Methods: Relevant data were collected from 40 healthy check-ups, 40 non-septic patients admitted to the ICU ward and 60 septic patients attending the First Affiliated Hospital of Dali University from September 2020 to September 2021, and subsequently divided into survival groups (n = 36) and death group (n = 24) according to the prognosis of septic patients, and compared PCT water in different groups. Results: PCT levels were significantly higher in the sepsis group than in the case- control and healthy control groups (P < 0.05) and in the sepsis death group (P < 0.05);subject work characteristic (ROC) curve analysis showed that PCT has a high value for diagnostic performance and prognostic judgment of sepsis. Conclusion: PCT has better diagnostic efficacy for sepsis and higher predictive value for its prognosis, which lays the foundation for further clinical application.