多囊卵巢综合征与代谢综合征相关研究进展

Research Progress of Polycystic Ovary Syndrome and Metabolic Syndrome

多囊卵巢综合征(polycystic ovarian syndrome, PCOS)是育龄期妇女常见的一种异质性内分泌疾病,发病原因复杂,且发病机制尚不明确。代谢综合征(metabolic syndrome, MS)是一组以腹型肥胖、空腹血糖受损、高血压、血脂异常为特征的代谢紊乱症候群。二者的临床表现有着高度的相似性,它们之间的关系至今尚不明确。PCOS合并代谢综合征时可增加心血管疾病和II型糖尿病发生的风险。而代谢综合征的诊断标准并不统一,所以对于PCOS合并代谢综合征的识别显得尤为重要。本文通过对PCOS和代谢综合征的危险因素进行综述,进而分析二者间的联系,以便早期识别PCOS合并代谢综合征。

Polycystic ovary syndrome (PCOS) is a common heterogeneous endocrine disease in women of childbearing age, with complex causes and unclear pathogenesis. Metabolic syndrome (MS) is a metabolic disorder syndrome characterized by abdominal obesity, impaired fasting blood glucose, hypertension, and abnormal blood lipids. The clinical manifestations of the two are highly similar, and the relationship between them is still unclear. PCOS combined with metabolic syndrome can increase the risk of cardiovascular disease and type II diabetes. The diagnostic criteria for metabol-ic syndrome are not unified, so the recognition of PCOS combined with metabolic syndrome is par-ticularly important. This article reviews the risk factors of PCOS and metabolic syndrome, and ana-lyzes the relationship between the two in order to early identify PCOS combined with metabolic syndrome.