循环游离DNA在常见肿瘤中的临床应用进展

Advances in the Clinical Application of Circulating Cell-Free DNA in Common Tumors

循环游离DNA (cell-free DNA, cfDNA)容易采集和无创的优点使其在肿瘤早期诊断、良恶性鉴别、疗效检测、预后评价等临床应用中受到广泛的关注。此外,cfDNA还可以反映肿瘤大小、肿瘤转移等。为此,本文综述了cfDNA的临床应用,以期为临床疾病的诊断、疗效分析提供帮助。

The advantages of circulating cell-free DNA (cfDNA) are easy to collect and non-invasive, which has attracted extensive attention in clinical applications such as early tumor diagnosis, benign and ma-lignant identification, efficacy detection, and prognosis evaluation. In addition, cfDNA can also re-flect tumor size, tumor metastasis, etc. Therefore, this article reviews the clinical application of cfDNA, in order to provide help for the diagnosis and efficacy analysis of clinical diseases.