顺磁性纳米材料用于T₁核磁共振成像的研究进展

The Research Advances on Paramagnetic Nanomaterials for T₁ MRI

核磁共振成像技术(MRI)由于其高空间分辨率,无电离辐射,临床实用性广等特点受到了海内外科研工作者的广泛关注。作为核磁造影剂的一种,T1核磁造影剂能够使目标区域信号增强,极大地提高了MRI的精确性和特异性,从而使临床医务人员能更好地辨别正常部位与患病部位的成像对比度,判断体内器官的功能状态。在本文中,我们讨论了当前研究得比较多的几种T1造影剂的研究进程以及其未来发展方向。

Magnetic resonance imaging (MRI) has been widely studied by researchers at home and abroad due to its high spatial resolution, no ionizing radiation and wide clinical practicability. As a kind of MRI contrast agent, T1 MRI contrast agent can enhance the target signal, greatly improving the accuracy and specificity of MRI, so that the clinical medical staff can better identify the image contrast between the normal position and the diseased parts, and determine the internal organs function. In this article, we discuss the research progress of several T1 contrast agents and its future development.