聚碳酸丙烯酯/醋酸纤维素纳米复合膜的制备及其抗菌性研究

Preparation and Antibacterial Study of Polycarbonate Propylene Ester/Cellulose Acetate Nanocomposite Membrane

聚碳酸丙烯酯(PPC)作为一种双向环保材料,具有原料种类繁、环保、生物相容性好等优点,在医用材料中具有广阔的应用前景。但存在热稳定性差、表面疏水性差等问题。为了增强PPC的热稳定性与抗菌性,本研究将醋酸纤维素(CA)纤维与PPC纤维复合,再将磺胺嘧啶银(SS)加入到PPC组分中,通过共轭纺丝的方法制备了PPC(SS)/CA三元复合纤维膜。所制备的纤维膜最大可承受344℃高温,比较纯PPC纤维膜的最大耐热温度226℃提升了118℃,并有优异的抗菌性能,对金黄色葡萄球菌的抑菌率均达到99%,这使得所制备的复合纤维膜在伤口敷料领域具有广阔的应用前景。

Polypropylene carbonate (PPC), as a bi-directional environmentally friendly material, has the advantages of a wide variety of raw materials, environmental friendliness, and good biocompatibility, and has broad application prospects in medical materials. But there are problems such as poor thermal stability and poor surface hydrophobicity. In order to enhance the thermal stability and antimicrobial properties of PPC, in this study, PPC(SS)/CA ternary composite fibrous membranes were prepared by conjugate spinning method by compositing cellulose acetate (CA) fibers with PPC fibers, and then incorporating silver sulfadiazine (SS) into the PPC component. The prepared fiber membrane can withstand a maximum high temperature of 344˚C, which is 118˚C higher than the maximum heat resistance temperature of a pure PPC fiber membrane of 226˚C. It also has excellent antibacterial performance, with an inhibition rate of 99% against Staphylococcus aureus. This makes the prepared composite fiber membrane have broad application prospects in the field of wound dressings.