社会支持对COPD患者自我效能、肺功能及生活质量影响的Meta分析

Influence of Social Support on Self-Efficacy, Pulmonary Function and Quality of Life in Patients with COPD: A Meta-Analysis

目的:通过系统评价分析社会支持对COPD患者自我效能、肺功能及生活质量的影响。方法:检索Cochrane Library、PubMed、Web of Science、Embase、中国知网、万方和生物医学文献数据库中关于社会支持对COPD患者的临床随机对照试验,检索时限从建库至2023年05月。对最终纳入的文献采用Cochrane风险偏倚评估工具进行质量评价,采用Revman5.3软件进行分析并绘图。这一系统评价已在PROSPERO (CRD42022372996)上注册。结果:最后纳入16篇文献,其中,英文2篇,中文14篇,共1455例患者。Meta分析结果显示,在对照组的基础上采用社会支持干预,自我效能(MD = 1.05, 95% CI 0.94~1.16, Z = 18.63, P < 0.00001);肺功能FEV1水平(MD = 0.27, 95% CI 0.21~0.32, Z = 9.02, P < 0.00001);SF-36QOL生活质量(MD = 10.21, 95% CI 8.99~11.44, Z = 16.34, P < 0.00001),与对照组相比差异均具有统计学意义(P < 0.05);SGRQ生活质量(MD = −1.99, 95% CI −4.22~0.24, Z = 1.75, P = 0.08);与对照组相比差异具有统计学意义(P < 0.1)。结论:对COPD的患者采用社会支持进行干预,能有效提高自我效能水平,改善肺功能FEV1,提高生活质量。

Objective: To systematically evaluate the influence of social support on self-efficacy, pulmonary function and quality of life in patients with chronic obstructive pulmonary disease (COPD). Methods: The Cochrane Library, Pub Med, Web of Science, Embase, CNKI, Wanfang Databases and Biomedical Literature Databases were searched for clinical randomized controlled trials about social support for patients with COPD, with the search time frame from the establishment of the database to May 2023. The quality of the included literature was evaluated using the Cochrane Library systematic review criteria and analyzed using Revman 5.3 software. This systematic evaluation was registered with PROSPERO (CRD42022372996). Results: Finally, sixteen articles were included, including 2 in English and 14 in Chinese, with a total of 1455 patients. Metaanalysis results showed that social support intervention based on the control group, there were significant differences in self-efficacy (MD = 1.05, 95% CI 0.94 to 1.16, Z = 18.63, P < 0.00001);FEV1 (MD = 0.27, 95% CI 0.21 to 0.32, Z = 9.02, P < 0.00001);SF-36QOL (MD = 10.21, 95% CI 8.99 to 11.44, Z = 16.34, P < 0.00001), P < 0.05;SGRQ (MD = −1.99, 95% CI −4.22 to 0.24, Z = 1.75, P = 0.08 ), P < 0.1. Conclusion: Social support is effective in increasing self-efficacy levels, improving pulmonary function FEV1 and improving quality of life in patients with COPD.