血管钙化的发生机制

The Mechanisms of Vascular Calcification

血管钙化是与骨发育相似的、主动的、高度可调控的复杂病理过程,主要表现为血管壁僵硬度增加和顺应性降低,是心血管疾病高发病率和高死亡率的重要原因。本文详细介绍了血管钙化的分类、病理特点,并对血管钙化的相关机制进行阐述。

Vascular calcification is recognized as an active and highly regulated complex pathological pro-cess that is similar to skeletal bone formation, mainly manifested by increased vascular wall stiffness and decreased compliance. Vascular calcification contributes to high morbidity and mortality of cardiovascular disease. In this paper, the classification and pathological features of vascular calcification are introduced in detail, and the related mechanism of vascular calcifica-tion is expounded.