摘要
Irisin (鸢尾素)从最初被发现在脂肪细胞棕化过程中的作用后就一直被研究者们广泛关注。它在多种组织中均有表达,在运动后及二型糖尿病,孕期糖尿病患者中表达量发生变化。由于Irisin可以改善胰岛素抵抗,促进脂肪细胞棕化,故其在糖尿病及肥胖症治疗中具有应用潜力。Irisin在神经系统发育中具有重要作用,其含量与认知水平密切相关。本文就Irisin的发现及生理效应的研究展开综述。
Irisin has inspired great interests from scientists since it was discovered to be important for white fat browning. It is expressed in many different tissues and Irisin level has been shown to change after exercise and in Type 2 diabetes patients and gestational diabetes patients. Since Irisin improves insulin resistance and promotes fat browning, it has great potential in diabetes and obesity treatment. Irisin plays important role in nervous system development, and its level is closely related to cognitive level. This review summarizes the physiological effects of Irisin and its research progress.
出处
《自然科学》
2021年第1期147-153,共7页
Open Journal of Nature Science
