苍附苁仙汤对肾虚痰瘀型多囊卵巢综合征患者中医证候及糖代谢的影响

Effects of CangfuCongxian Decoction on TCM Syndrome and Glucose Metabolism in Polycystic Ovary Syndrome Patients with Kidney Deficiency and Phlegm Stasis

目的:观察苍附苁仙汤对肾虚痰瘀型多囊卵巢综合征患者中医证候以及糖代谢的影响。方法:对60例多囊卵巢综合征患者随机分为观察组和对照组,观察组服用苍附苁仙汤 + 二甲双胍3个月经周期,对照组服用二甲双胍3个月经周期,观察各组中医证候、体重指数(body mass index, BMI)、腰臀比(waist-hip ratio, WHR)以及糖代谢的变化。结果:观察组治疗后中医证候评分较对照组明显下降,差异具有统计学意义(P 0.05)。与对照组比较,观察组体重指数、空腹胰岛素水平及胰岛素抵抗指数均降低,差异具有统计学意义(P <0.05)。结论:苍附苁仙汤可以改善PCOS患者中医证候,改善机体糖代谢水平,与二甲双胍协同应用能够更好改善PCOS患者基础状态。

Objective:To observe the effect of CangfuCongxian decoction treatment on polycystic ovary syndrome(PCOS)patient of TCM Syndrome and Glucose Metabolism.Method:Patients with PCOS were divided into two groups randomly.The observation group took CangfuCongxian Decoction+metformin for three menstrual cycles,and the control group took metformin for three menstrual cycles.The changes of TCM syndromes,waist-hip ratio(WHR)and sugar metabolism were observed in each group.Results:After treatment,the scores of TCM syndromes in the observation group were significantly lower than those in the control group(P 0.05).Compared with the control group,the body mass index(BMI),fasting insulin level and insulin resistance index of the observation group were decreased,with statistical significance(P<0.05).Conclusion:CangfuCongxian Decoction can improve the TCM syndromes of PCOS patients,improve the body’s glucose metabolism level,and better improve the basic state of patients with metformin.