基于健脾为本治疗慢性萎缩性胃炎及癌前病变的研究

The Research of Chronic Atrophic Gastritis and Precancerous Lesions Based on Spleen-Strengthening Therapy

慢性萎缩性胃炎是以胃黏膜腺体萎缩为主要特征的常见消化系统疾病,常伴有胃黏膜肠上皮化生和异型增生,是胃癌前疾病之一。中医药在治疗胃癌前疾病方面具有明显的特色与优势。我们认为,脾虚证在慢性萎缩性胃炎及癌前疾病中极为常见,这一病机特点也是疾病发展与转归的关键所在。本文旨在介绍本研究团队基于健脾为本治疗慢性萎缩性胃炎及癌前病变近20年的临床与实验研究,提出脾虚为本是慢性萎缩性胃炎及癌前病变的病机特点,健脾为本是治疗慢性萎缩性胃炎及癌前病变的关键。

Chronic atrophic gastritis is a common digestive system disease characterized by gastric mucosal gland atrophy, and is often accompanied by gastric mucosa epithelium metaplasia and dysplasia. It is one of the pre-gastric cancer diseases. Traditional Chinese medicine has obvious characteristics and advantages in the treatment of pre-gastric cancer. We believe that spleen deficiency syndrome is very common in chronic atrophic gastritis and precancerous diseases, which is also the key to the development and prognosis of the disease. The aim of this paper is to introduce clinical and experimental studies of our research group in the treatment of chronic atrophic gastritis and precancerous lesions based on spleen-strengthening therapy for nearly 20 years. We suggested that the pathogenesis of chronic atrophic gastritis and precancerous lesions is spleen deficiency;therefore, strengthening the spleen is the key to treat chronic atrophic gastritis and precancerous lesions.