冬凌草资源评价和可持续利用研究现状与展望

Current Situation and Prospective on Resource Evaluation and Sustainable Utilization of Rabdosiae Rubescentis Herba

中药冬凌草为唇形科香茶菜属植物碎米桠Isodon rubescens (Hemsl.) Hara的干燥地上部分,其药理活性成分在临床上具有抗肿瘤、抗菌消炎的作用。冬凌草富含的冬凌草甲素、冬凌草乙素由于其显著的抗肿瘤活性近年来得到广泛关注。本文对我国冬凌草资源从种类与分布、化学成分及药理作用、药材质量评价、繁育栽培、分子生药学研究等方面进行了综述,提出了冬凌草可持续利用的综合建议,为冬凌草资源的保护、开发和利用以及综合评价,提供合理化参考。

The traditional Chinese medicine Rabdosiae Rubescentis Herba is the above-ground herbaceous part of Isodon rubescens (Hemsl.) Hara. Its pharmacologically active ingredients have clinically anti-tumor, anti-bacterial and anti-inflammatory effects. Oridonin and ponicidin, which are rich in Rabdosiae Rubescentis Herba, have received widespread attention in recent years due to their significant anti-tumor activity. This review focuses on the research progress of the resources of Rabdosiae Rubescentis Herba in our country on species and distribution, chemical components and pharmacological effects, quality evaluation of medicinal materials, breeding and cultivation, and molecular pharmacology, and puts forward comprehensive recommendations for the sustainable use of Rabdosiae Rubescentis Herba, to provide a reference for the protection, development and utilization, and the comprehensive evaluation of Rabdosiae Rubescentis Herba resources.